Article
Molecular and hematological profiles of hemoglobin EE disease with different forms of alpha-thalassemia.
Annals of hematology - 1 Jul 2006
Fucharoen Goonnapa, Trithipsombat Jaruwan, Sirithawee Suparerk, Yamsri Supawadee, Changtrakul Yossombat, Sanchaisuriya Kanokwan, Fucharoen Supan
Abstract excerpt
We describe hematologic and DNA characterization of hemoglobin (Hb) E homozygote with various forms of alpha-thalassemia in Thai individuals. Altogether, 131 unrelated adult subjects with Hb EE at routine Hb analysis were studied. Forty-two cases were found to carry alpha-thalassemia with ten different genotypes. These included 21 cases with alpha(+)-thalassemia heterozygote (-alpha(3.7)/alphaalpha), one case...
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