Article
Clinical and hematological phenotype of homozygous hemoglobin E: revisit of a benign condition with hidden reproductive risk.
The Southeast Asian journal of tropical medicine and public health - 1 Mar 2009
Tachavanich Kalaya, Viprakasit Vip, Chinchang Worawut, Glomglao Waraporn, Pung-Amritt Parichat, Tanphaichitr Voravarn S
Abstract excerpt
Hemoglobin E (HbE) is one of the most prevalent beta-globin variant, which is widely distributed in Southeast Asia especially in Thailand. Homozygosity for this variant is common and may occur with iron deficiency. In order to study clinical and hematological phenotypes without the confounding effect of iron deficiency, investigations were carried out before and after iron supplementation for 2 months. The effect...
Topics
- Anemia, Iron-Deficiency
- Enzyme-Linked Immunosorbent Assay
- Female
- Glucosephosphate Dehydrogenase
- Hemoglobin E
- Homozygote
- Humans
- Phenotype
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length
- Pregnancy
- Pregnancy Complications, Hematologic
- Risk