Article
Association between human leukocyte antigen class II and pulmonary tuberculosis due to mycobacterium tuberculosis in Uganda.
BMC infectious diseases - 23 Jan 2016
Wamala Dan, Buteme Helen Koyokoyo, Kirimunda Samuel, Kallenius Gunilla, Joloba Moses
Abstract excerpt
BACKGROUND: Mycobacterium tuberculosis (Mtb) is reported to infect about a third of the world's population but only 10% are thought to develop active tuberculosis (TB) disease. Host immunity regulated by human leukocyte antigens (HLA) is an important determinant of the outcome of the disease. Here we investigate HLA class II gene polymorphisms in susceptibility to TB, and whether particular HLA class II alleles...
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