Article
HLA class II alleles as markers of tuberculosis susceptibility and resistance.
Revista portuguesa de pneumologia - 1 Jan 2000
Duarte R, Carvalho C, Pereira C, Bettencourt A, Carvalho A, Villar M, Domingos A, Barros H, Marques Ja, Pinho Costa P, Mendonça D, Martins B
Abstract excerpt
BACKGROUND: Not every individual exposed to Mycobacterium tuberculosis becomes infected. One host genetic factor, involved in modulating the immune response that has been studied in many ethnic groups is the association of human leukocyte antigens (HLA) with susceptibility to tuberculosis (TB). OBJECTIVE: To investigate the association between TB, HLA-DRB1 and HLA-DQB1 alleles in a Portuguese population. METHODS:...
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