Use of noise in gene expression as an experimental parameter to test phenotypic effects.

Abstract excerpt

During the last decade, the molecular basis for gene expression noise has been mostly deciphered, helping understanding of how gene regulation is controlled and how the generation of cell-cell non-genetic heterogeneity is modulated through noise. In the same period, the functional importance of phenotypic heterogeneity among cell populations has been recognized and widely involved in major biological phenomena....

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