Article
Using gene expression noise to understand gene regulation.
Science (New York, N.Y.) - 13 Apr 2012
Munsky Brian, Neuert Gregor, van Oudenaarden Alexander
Abstract excerpt
Phenotypic variation is ubiquitous in biology and is often traceable to underlying genetic and environmental variation. However, even genetically identical cells in identical environments display variable phenotypes. Stochastic gene expression, or gene expression "noise," has been suggested as a major source of this variability, and its physiological consequences have been topics of intense research for the last...
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