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Article

Fitness effects of altering gene expression noise in Saccharomyces cerevisiae.

eLife - 20 Aug 2018

Duveau Fabien, Hodgins-Davis Andrea, Metzger Brian Ph, Yang Bing, Tryban Stephen, Walker Elizabeth A, Lybrook Tricia, Wittkopp Patricia J

Abstract excerpt

Gene expression noise is an evolvable property of biological systems that describes differences in expression among genetically identical cells in the same environment. Prior work has shown that expression noise is heritable and can be shaped by selection, but the impact of variation in expression noise on organismal fitness has proven difficult to measure. Here, we quantify the fitness effects of altering...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 30124429
DOI: 10.7554/eLife.37272
PMCID: PMC6133559

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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