Article
FKBP5 modulates the hippocampal connectivity deficits in depression: a study in twins.
Brain imaging and behavior - 1 Feb 2017
Córdova-Palomera Aldo, de Reus Marcel A, Fatjó-Vilas Mar, Falcón Carles, Bargalló Nuria, van den Heuvel Martijn P, Fañanás Lourdes
Abstract excerpt
The hippocampus is a key modulator of stress responses underlying depressive behavior. While FKBP5 has been found associated with a large number of stress-related outcomes and hippocampal features, its potential role in modifying the hippocampal communication transfer mechanisms with other brain regions remains largely unexplored. The putative genetic or environmental roots of the association between depression...
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