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Article

The NPC1L1 Polymorphism 1679C>G Is Associated with Gallstone Disease in Chinese Patients.

PloS one - 1 Jan 2016

Wu Jian, Cui Wei, Cai Qu, Fei Jian, Zhang Sheng-Dao, Han Tian-Quan, Hu Hai, Jiang Zhao-Yan

Abstract excerpt

Niemann Pick Type C1 Like 1 (NPC1L1) protein plays a key role in intestinal and hepatic cholesterol metabolism in humans. Genetic variation in NPC1L1 has been widely studied in recent years. We analyzed NPC1L1 single nucleotide polymorphisms in Chinese gallstone disease patients to investigate their association with gallstone disease. NPC1L1 mRNA expression was also measured in liver biopsies from patients with...

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Identifiers

PMID: 26800364
DOI: 10.1371/journal.pone.0147562
PMCID: PMC4723254

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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