Genetic variations of the NPC1L1 gene associated with hepatitis C virus (HCV) infection and biochemical characteristics of HCV patients in China.

doi:10.1016/j.ijid.2016.10.007

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Article

Genetic variations of the NPC1L1 gene associated with hepatitis C virus (HCV) infection and biochemical characteristics of HCV patients in China.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases - 1 Dec 2016

Zhang A-Mei, Zhang Cheng-Lin, Song Yuzhu, Zhao Ping, Feng Yue, Wang Binghui, Li Zheng, Liu Li, Xia Xueshan

Abstract excerpt

OBJECTIVES: About 2% of the world population is infected with hepatitis C virus (HCV), a leading cause of hepatic cirrhosis and hepatocellular carcinoma. The Niemann-Pick C1-like 1 cholesterol absorption receptor (NPC1L1) was recently identified to be an important factor for HCV entry into host c...

Topics

Adult
Alleles
Carcinoma, Hepatocellular
China
Female
Genetic Predisposition to Disease
Genetic Variation
Genotype
Haplotypes
Hepacivirus
Hepatitis C
Humans
Linkage Disequilibrium
Liver Cirrhosis

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Liver Neoplasms

Male

Membrane Proteins

Membrane Transport Proteins

Source

Open in PubMed

Identifiers

PMID: 27769799
DOI: 10.1016/j.ijid.2016.10.007

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-27769799-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.