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Article

Genetic variations of the NPC1L1 gene associated with hepatitis C virus (HCV) infection and biochemical characteristics of HCV patients in China.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases - 1 Dec 2016

Zhang A-Mei, Zhang Cheng-Lin, Song Yuzhu, Zhao Ping, Feng Yue, Wang Binghui, Li Zheng, Liu Li, Xia Xueshan

Abstract excerpt

OBJECTIVES: About 2% of the world population is infected with hepatitis C virus (HCV), a leading cause of hepatic cirrhosis and hepatocellular carcinoma. The Niemann-Pick C1-like 1 cholesterol absorption receptor (NPC1L1) was recently identified to be an important factor for HCV entry into host cells. Whether genetic variations of the NPC1L1 gene are associated with HCV infection is unknown. METHODS: In this...

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PMID: 27769799
DOI: 10.1016/j.ijid.2016.10.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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