Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Positive selection and high sensitivity test for MYD88 mutations using locked nucleic acid.

International journal of laboratory hematology - 1 Apr 2016

Albitar A, Ma W, DeDios I, Estella J, Agersborg S, Albitar M

Abstract excerpt

INTRODUCTION: Detection of mutations in the myeloid differentiation primary response gene 88 (MYD88) has clinical implications on diagnosis and therapy, especially in patients with Waldenström's macroglobulinemia (WM) and IgM monoclonal gammopathy of unknown significance (IgM-MGUS). We describe a method that provides greatly increased sensitivity for detecting minority mutations in MYD88. METHODS: We used a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over
Share to DNA Mutational Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Monoclonal Gammopathy of Undetermined Significance

Share to Myeloid Differentiation Factor 88

Share to Oligonucleotides

Share to Reproducibility of Results

Share to Sensitivity and Specificity

Share to Waldenstrom Macroglobulinemia

Source

Identifiers

PMID: 26797804
DOI: 10.1111/ijlh.12456

Genes

MYD88

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Positive selection and high sensitivity test for MYD88 mutations using locked nucleic acid.PMID 26797804Read ↗

Wild-type Blocking PCR Combined with Direct Sequencing as a Highly Sensitive Method for Detection of Low-Frequency Somatic Mutations.Semantic proximity Read ↗

MYD88 L265P in Waldenström macroglobulinemia, immunoglobulin M monoclonal gammopathy, and other B-cell lymphoproliferative disorders using conventional and quantitative allele-specific polymerase chain reaction.Semantic proximity Read ↗

MYD88 Mutations: Transforming the Landscape of IgM Monoclonal Gammopathies.Semantic proximity Read ↗

Diagnostic Next-generation Sequencing Frequently Fails to Detect MYD88L265P in Waldenström MacroglobulinemiaSemantic proximity Read ↗

Rapid and highly sensitive detection of MYD88/CXCR4 mutations in Waldenström macroglobulinemia by MAS-qPCR: A pilot study.Semantic proximity Read ↗

MYD88 and beyond: novel opportunities for diagnosis, prognosis and treatment in Waldenström's Macroglobulinemia.Semantic proximity Read ↗

PlentiPlex™ MYD88 Waldenström lymphoma qPCR assay: A highly sensitive method for detection of MYD88 L265P mutation.Semantic proximity Read ↗

Determination of MYD88 and CXCR4 Mutations for Clinical Detection and Their Significance in Waldenström Macroglobulinemia.Semantic proximity Read ↗

Prognostic impact of MYD88 and CXCR4 mutations assessed by droplet digital polymerase chain reaction in IgM monoclonal gammopathy of undetermined significance and smouldering Waldenström macroglobulinaemia.Semantic proximity Read ↗

MYD88 wild-type Waldenstrom Macroglobulinaemia: differential diagnosis, risk of histological transformation, and overall survival.Semantic proximity Read ↗

[Exploring the detection of MYD88 mutation in patients with Waldenström macroglobulinemia by different methods and specimens].Semantic proximity Read ↗

Selective amplification of rare mutations using locked nucleic acid oligonucleotides that competitively inhibit primer binding to wild-type DNA.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.