Article
MYD88 wild-type Waldenstrom Macroglobulinaemia: differential diagnosis, risk of histological transformation, and overall survival.
British journal of haematology - 1 Feb 2018
Treon Steven P, Gustine Joshua, Xu Lian, Manning Robert J, Tsakmaklis Nicholas, Demos Maria, Meid Kirsten, Guerrera Maria L, Munshi Manit, Chan Gloria, Chen Jiaji, Kofides Amanda, Patterson Christopher J, Yang Guang, Liu Xia, Severns Patricia, Dubeau Toni, Hunter Zachary R, Castillo Jorge J
Abstract excerpt
MYD88 mutations are present in 95% of Waldenstrom Macroglobulinaemia (WM) patients, and support diagnostic discrimination from other IgM-secreting B-cell malignancies. Diagnostic discrimination can be difficult among suspected wild-type MYD88 (MYD88WT ) WM cases. We systematically reviewed the clinical, pathological and laboratory studies for 64 suspected MYD88WT WM patients. World Health Organization and WM...
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