Article
Alteration of Natural Killer cell phenotype and function in obese individuals.
Clinical immunology (Orlando, Fla.) - 1 Apr 2017
Viel Sébastien, Besson Laurie, Charrier Emily, Marçais Antoine, Disse Emmanuel, Bienvenu Jacques, Walzer Thierry, Dumontet Charles
Abstract excerpt
Obesity is associated with increased cancer rates and higher susceptibility to infections. The adipose tissue of obese individuals is inflammatory and may negatively impact on innate and adaptive immunity in a systemic way. Here, we explored the phenotype and function of peripheral Natural Killer (NK) cells of patients in correlation with their body mass index (BMI). We found that high BMI was associated with an...
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