Article
The Problem of Borderline Hemoglobin A2 Levels in the Screening for β-Thalassemia Carriers in Sardinia.
Acta haematologica - 1 Jan 2016
Paglietti Maria Elisabetta, Satta Stefania, Sollaino Maria Carla, Barella Susanna, Ventrella Arianna, Desogus Maria Franca, Demartis Franca Rosa, Manunza Laura, Origa Raffaella
Abstract excerpt
BACKGROUND: The increase in HbA2 is the most important parameter for the identification of thalassemia carriers. However, in routine screening for hemoglobinopathies, some cases are difficult to classify because the level of HbA2 is not typically elevated. In this work, we report the results of a molecular investigation on a cohort of subjects with borderline HbA2. METHODS: All subjects with a β-thalassemia...
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