Article
Delineation of the molecular basis of borderline hemoglobin A2 in Chinese individuals.
Blood cells, molecules & diseases - 1 Dec 2014
Lou Ji-Wu, Li Dong-Zhi, Zhang Yu, He Yi, Sun Man-Na, Ye Wan-Ling, Liu Yan-Hui
Abstract excerpt
BACKGROUND: The "gray zone" of borderline hemoglobin A2 (Hb A2) may be present in a large section of the population, especially in countries where thalassemia is common. However, very little is currently known of the molecular basis of borderline Hb A2 in Chinese individuals. METHOD: In this study, we performed a comprehensive analysis of the globin genotypes and KLF1 gene mutations associated with borderline Hb...
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