Article
The significance of the hemoglobin A(2) value in screening for hemoglobinopathies.
Clinical biochemistry - 1 Dec 2009
Giambona Antonino, Passarello Cristina, Renda Disma, Maggio Aurelio
Abstract excerpt
BACKGROUND AND OBJECTIVE: The inherited hemoglobinopathies are a large group of disorders that include thalassemias and hemoglobin variants. Accurate determination of the carrier phenotype is essential for detecting couples at risk for producing offspring with hemoglobinopathy. Heterozygous beta-thalassemia is usually silent at the clinical level. His phenotype is characterized by microcytosis and hypochromia...
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