Article

Antipsychotic Use in Bipolar Disorder: Clinical and Genomic Correlates– A Mayo Clinic Bipolar Disorder Biobank Study

2025-08-05

Abstract excerpt

<title>Abstract</title> <p> <bold>Background:</bold> Responsiveness to mood-stabilizing pharmacotherapy varies in bipolar disorder (BD). We investigated clinical correlates of second-generation antipsychotic (SGA) treatment response and conducted the first genome-wide association study (GWAS), including exploratory polygenic scores (PGS), of SGA pharmacogenomic treatment response in BD. <bold>Methods:</bold>...

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Literature Corpus work: be1a78c1-8243-575b-8210-a1fb9c5cc4b7
DOI: 10.21203/rs.3.rs-7274612/v1

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