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Article

Predicting chemotherapeutic drug combinations through gene network profiling.

Scientific reports - 21 Jan 2016

Nguyen Thi Thuy Trang, Chua Jacqueline Kia Kee, Seah Kwi Shan, Koo Seok Hwee, Yee Jie Yin, Yang Eugene Guorong, Lim Kim Kiat, Pang Shermaine Yu Wen, Yuen Audrey, Zhang Louxin, Ang Wee Han, Dymock Brian, Lee Edmund Jon Deoon, Chen Ee Sin

Abstract excerpt

Contemporary chemotherapeutic treatments incorporate the use of several agents in combination. However, selecting the most appropriate drugs for such therapy is not necessarily an easy or straightforward task. Here, we describe a targeted approach that can facilitate the reliable selection of chemotherapeutic drug combinations through the interrogation of drug-resistance gene networks. Our method employed...

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Identifiers

PMID: 26791325
DOI: 10.1038/srep18658
PMCID: PMC4726371

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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