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Article

The fruRBA Operon Is Necessary for Group A Streptococcal Growth in Fructose and for Resistance to Neutrophil Killing during Growth in Whole Human Blood.

Infection and immunity - 1 Apr 2016

Valdes Kayla M, Sundar Ganesh S, Vega Luis A, Belew Ashton T, Islam Emrul, Binet Rachel, El-Sayed Najib M, Le Breton Yoann, McIver Kevin S

Abstract excerpt

Bacterial pathogens rely on the availability of nutrients for survival in the host environment. The phosphoenolpyruvate-phosphotransferase system (PTS) is a global regulatory network connecting sugar uptake with signal transduction. Since the fructose PTS has been shown to impact virulence in several streptococci, including the human pathogen Streptococcus pyogenes(the group A Streptococcus[GAS]), we...

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Identifiers

PMID: 26787724
DOI: 10.1128/IAI.01296-15
PMCID: PMC4807502

Genes

PTS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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