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Article

Analysis of two-component systems in group B Streptococcus shows that RgfAC and the novel FspSR modulate virulence and bacterial fitness.

mBio - 20 May 2014

Faralla Cristina, Metruccio Matteo M, De Chiara Matteo, Mu Rong, Patras Kathryn A, Muzzi Alessandro, Grandi Guido, Margarit Immaculada, Doran Kelly S, Janulczyk Robert

Abstract excerpt

UNLABELLED: Group B Streptococcus (GBS), in the transition from commensal organisms to pathogens, will encounter diverse host environments and, thus, require coordinated control of the transcriptional responses to these changes. This work was aimed at better understanding the role of two-component signal transduction systems (TCS) in GBS pathophysiology through a systematic screening procedure. We first performed...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24846378
DOI: 10.1128/mBio.00870-14
PMCID: PMC4030450

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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