Article

FRUCTOSE ACTIVATES A STRESS RESPONSE SHARED BY METHYLGLYOXAL AND HYDROGEN PEROXIDE IN <i>STREPTOCOCCUS MUTANS</i>

2024-10-27

Abstract excerpt

Fructose catabolism by Streptococcus mutans is initiated by three PTS transporters yielding fructose-1-phoshate (F-1-P) or fructose-6-phosphate. Deletion of one such F-1-P-generating PTS, fruI , was shown to reduce the cariogenicity of S. mutans in rats fed a high-sucrose diet. Moreover, a recent study linked fructose metabolism in S. mutans to a reactive electrophile species (RES) methylglyoxal. Here, we cond...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: f6ad4333-7ed9-5069-8928-9ecdbaff3e7e
DOI: 10.1101/2024.10.26.620100

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

FRUCTOSE ACTIVATES A STRESS RESPONSE SHARED BY METHYLGLYOXAL AND HYDROGEN PEROXIDE IN <i>STREPTOCOCCUS MUTANS</i>DOI 10.1101/2024.10.26.620100Read

Essential Roles of the <i>SPPRA</i> Fructose-Phosphate Phosphohydrolase Operon in Carbohydrate Metabolism and Virulence Expression by <i>Streptococcus Mutans</i>Semantic proximity Read

Genetic Characterization of Glyoxalase Pathway in Oral Streptococci and its Contribution to Interbacterial CompetitionSemantic proximity Read

Analysis of the <i>Streptococcus mutans</i> proteome during acid and oxidative stress reveals modules of co-expression and an expanded role for the TreR transcriptional regulatorSemantic proximity Read

Glucose PTS Modulates Pyruvate Metabolism, Bacterial Fitness, and Microbial Ecology in Oral StreptococciSemantic proximity Read

SMU_1361c regulates the oxidative stress response of <i>Streptococcus mutans</i>Semantic proximity Read

Sucrose- and Fructose-Specific Effects on the Transcriptome of Streptococcus mutans, as Determined by RNA SequencingSemantic proximity Read

Amino Sugars Reshape Interactions between <i>Streptococcus mutans</i> and <i>Streptococcus gordonii</i>Semantic proximity Read

Regulatory involvement of the PerR and SloR metalloregulators in the <i>Streptococcus mutans</i> oxidative stress responseSemantic proximity Read

Spontaneous Mutants of <i>Streptococcus sanguinis</i> with Defects in the Glucose-PTS Show Enhanced Post-Exponential Phase FitnessSemantic proximity Read

The Biology of Streptococcus mutansSemantic proximity Read

Genetic variability of mutans streptococci revealed by wide whole-genome sequencing.Semantic proximity Read

Glycerol Metabolism Contributes to Competition by Oral Streptococci through Production of Hydrogen PeroxideSemantic proximity Read