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Article

Intrinsic Disorder-Based Design of Stabilizing Disulphide Bridge in Gαo Protein.

Protein and peptide letters - 1 Jan 2016

Nagibina Galina S, Tin Ulyana F, Glukhov Anatoly S, Melnik Tatiana N, Melnik Bogdan S

Abstract excerpt

In this study, we have used an approach that allows us to determine in what region of the polypeptide chain of protein it is required to insert a disulphide bond in order to stabilize it. In our previous paper [Melnik et al., JBSD. 2012] it was proposed that to search for a "weak" site in the protein, it is possible to use programs (for example, PONDR-FIT and IsUnstruct) finding intrinsic disorder protein...

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PMID: 26786871
DOI: 10.2174/092986652302160105130540

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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