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Article

Are the parameters of various stabilization factors estimated from mutant human lysozymes compatible with other proteins?

Protein engineering - 1 Feb 2001

Funahashi J, Takano K, Yutani K

Abstract excerpt

The various factors which contribute to protein stability have been extensively examined using mutant proteins, but the same kinds of substitutions have given different results depending on the substitution sites. Recently, the contributions of some stabilization factors have been quantitatively derived as parameters by a unique equation, considering the conformational changes due to the mutations using mutant...

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PMID: 11297670
DOI: 10.1093/protein/14.2.127

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