Article
The folding pathway of a single domain in a multidomain protein is not affected by its neighbouring domain.
Journal of molecular biology - 25 Apr 2008
Batey Sarah, Clarke Jane
Abstract excerpt
Domains are the structural, functional, and evolutionary components of proteins. Most folding studies to date have concentrated on the folding of single domains, but more than 70% of human proteins contain more than one domain, and interdomain interactions can affect both the stability and the fo...
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