Article
Roles of aquaporin-4 isoforms and amino acids in square array assembly.
Biochemistry - 30 Jun 2009
Strand Line, Moe Svein Erik, Solbu Tom Tallak, Vaadal Marianne, Holen Torgeir
Abstract excerpt
Aquaporin-4 (AQP4) is a water channel found at high concentrations around blood vessels in the brain and is organized into elaborate assemblies called square arrays. The natural functions of AQP4 and the square arrays remain unknown, but under pathophysiological conditions, AQP4 has been shown to influence brain edema, synapse function, and cellular migration. AQP4 was recently found to have six isoforms, where...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.