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Article

Identification of novel noncoding transcripts in telomerase-negative yeast using RNA-seq.

Scientific reports - 20 Jan 2016

Niederer Rachel O, Papadopoulos Nickolas, Zappulla David C

Abstract excerpt

Telomerase is a ribonucleoprotein that maintains the ends of linear chromosomes in most eukaryotes. Loss of telomerase activity results in shortening of telomeric DNA and eventually a specific G2/M cell-cycle arrest known as senescence. In humans, telomere shortening occurs during aging, while inappropriate activation of telomerase is associated with approximately 90% of cancers. Previous studies have identified...

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Share to Cellular Senescence
Share to Epistasis, Genetic
Share to Gene Expression Regulation, Fungal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to RNA, Long Noncoding

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Source

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Identifiers

PMID: 26786024
DOI: 10.1038/srep19376
PMCID: PMC4726298

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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