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Article

Induction of global stress response in Saccharomyces cerevisiae cells lacking telomerase.

Biochemical and biophysical research communications - 1 Mar 2002

Teng Shu-Chun, Epstein Charles, Tsai Yun-Luen, Cheng Hui-Wen, Chen Hung-Lin, Lin Jing-Jer

Abstract excerpt

Cellular senescence is a major intermediate step from healthy cells toward tumor cells. By using microarrays that simultaneously examine the transcription levels of 6,200 Saccharomyces cerevisiae genes, we show that 45 gene transcript levels are increased and 11 are decreased after exposure to telomere shortening and cellular senescence in a telomerase-deficient mutant. About half of the genes that showed...

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Source

Identifiers

PMID: 11855849
DOI: 10.1006/bbrc.2002.6509

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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