Article
Defining macrophage phenotype and function in adipose tissue.
Trends in immunology - 1 Jul 2011
Dalmas Elise, Clément Karine, Guerre-Millo Michèle
Abstract excerpt
In obesity, chronic low-grade inflammation is thought to mediate the effects of increased adipose tissue mass on metabolic comorbidity. Of the different cell types that contribute to obesity-induced inflammation in adipose tissue, this review focuses on macrophages and their monocytes precursors. Mechanisms for monocyte recruitment to adipose tissue, and how both monocytes and macrophages are phenotypically...
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