Adipose tissue macrophages: phenotypic plasticity and diversity in lean and obese states.

doi:10.1097/MCO.0b013e328347970b

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Article

Adipose tissue macrophages: phenotypic plasticity and diversity in lean and obese states.

Current opinion in clinical nutrition and metabolic care - 1 Jul 2011

Morris David L, Singer Kanakadurga, Lumeng Carey N

Abstract excerpt

PURPOSE OF REVIEW: Proinflammatory adipose tissue macrophages (ATMs) contribute to obesity-associated disease morbidity. We will provide an update of the current state of knowledge regarding the phenotypic and functional diversity of ATMs in lean and obese mice and humans. RECENT FINDINGS: The phenotypic diversity of ATMs is now known to include more than two types requiring an expansion of the simple concept of...

Topics

Adipose Tissue
Animals
CD11c Antigen
Ceramides
Fibrosis
Humans
Inflammation
Lectins, C-Type
Lipodystrophy
Lipolysis
Macrophages
Mannose Receptor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mannose-Binding Lectins

Mice

Mice, Obese

Obesity

Phenotype

Receptors, Cell Surface

Source

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PMID: 21587064
DOI: 10.1097/MCO.0b013e328347970b
PMCID: PMC4690541

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