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Article

Adipocyte-derived PAMM suppresses macrophage inflammation by inhibiting MAPK signalling.

The Biochemical journal - 15 Dec 2015

Guo Fang, He Hui, Fu Zhi-Chao, Huang Shengping, Chen Tingtao, Papasian Christopher J, Morse Leslie R, Xu Yan, Battaglino Ricardo A, Yang Xiao-Feng, Jiang Zhisheng, Xin Hong-Bo, Fu Mingui

Abstract excerpt

Macrophages within adipose tissue play a key role in mediating inflammatory responses in adipose tissue that are associated with obesity-related metabolic complications. In an effort to identify novel proteins secreted from adipocytes that may negatively regulate macrophage inflammation, we found that peroxiredoxin (PRX)-like 2 activated in M-CSF stimulated monocytes (PAMM), a CXXC-type PRX-like 2...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26438880
DOI: 10.1042/BJ20150019
PMCID: PMC4754088

Genes

PRX

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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