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Article

Genetic Determinants of Thrombin Generation and Their Relation to Venous Thrombosis: Results from the GAIT-2 Project.

PloS one - 1 Jan 2016

Martin-Fernandez Laura, Ziyatdinov Andrey, Carrasco Marina, Millon Juan Antonio, Martinez-Perez Angel, Vilalta Noelia, Brunel Helena, Font Montserrat, Hamsten Anders, Souto Juan Carlos, Soria José Manuel

Abstract excerpt

BACKGROUND: Venous thromboembolism (VTE) is a common disease where known genetic risk factors explain only a small portion of the genetic variance. Then, the analysis of intermediate phenotypes, such as thrombin generation assay, can be used to identify novel genetic risk factors that contribute to VTE. OBJECTIVES: To investigate the genetic basis of distinct quantitative phenotypes of thrombin generation and its...

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Identifiers

PMID: 26784699
DOI: 10.1371/journal.pone.0146922
PMCID: PMC4718515

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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