Article
Genome-wide linkage scan in affected sibling pairs identifies novel susceptibility region for venous thromboembolism: Genetics In Familial Thrombosis study.
Journal of thrombosis and haemostasis : JTH - 1 Aug 2013
de Visser M C H, van Minkelen R, van Marion V, den Heijer M, Eikenboom J, Vos H L, Slagboom P E, Houwing-Duistermaat J J, Rosendaal F R, Bertina R M
Abstract excerpt
BACKGROUND: Venous thromboembolism (VTE) is a multicausal disorder involving environmental and genetic risk factors. In many thrombophilic families the clustering of thrombotic events cannot be explained by known genetic risk factors, indicating that some remain to be discovered. OBJECTIVES: We aimed to identify novel thrombosis susceptibility alleles in a large panel of small thrombophilic families: the Genetics...
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