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Article

PANCR, the PITX2 Adjacent Noncoding RNA, Is Expressed in Human Left Atria and Regulates PITX2c Expression.

Circulation. Arrhythmia and electrophysiology - 1 Jan 2016

Gore-Panter Shamone R, Hsu Jeffrey, Barnard John, Moravec Christine S, Van Wagoner David R, Chung Mina K, Smith Jonathan D

Abstract excerpt

BACKGROUND: Genome-wide studies reveal that genetic variants at chromosome 4q25 constitute the strongest locus associated with atrial fibrillation, the most frequent arrhythmia. However, the mechanisms underlying this association are unknown. Our goal is to find and characterize left atrial-expressed transcripts in the chromosome 4q25 atrial fibrillation risk locus that may play a role in atrial fibrillation...

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Topics

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Share to Atrial Fibrillation
Share to Gene Expression Regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Heart Atria

Share to Homeobox Protein PITX2

Share to Homeodomain Proteins

Share to Myocytes, Cardiac

Share to Reverse Transcriptase Polymerase Chain Reaction

Share to RNA, Untranslated

Source

Open in PubMed Open full text

Identifiers

PMID: 26783232
DOI: 10.1161/CIRCEP.115.003197
PMCID: PMC4719779

Genes

PITX2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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PANCR, the PITX2 Adjacent Noncoding RNA, Is Expressed in Human Left Atria and Regulates PITX2c Expression.PMID 26783232Read ↗

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