Generalization of Rare Variant Association Tests for Longitudinal Family Studies.

Abstract excerpt

Given the functional relevance of many rare variants, their identification is frequently critical for dissecting disease etiology. Functional variants are likely to be aggregated in family studies enriched with affected members, and this aggregation increases the statistical power to detect rare variants associated with a trait of interest. Longitudinal family studies provide additional information for...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Black or African American
• Share to Cardiovascular Diseases
• Share to Exome