Article
Association between TAP1 gene polymorphisms and alopecia areata in a Korean population.
Genetics and molecular research : GMR - 29 Dec 2015
Kim H K, Lee H, Lew B L, Sim W Y, Kim Y O, Lee S W, Lee S, Cho I K, Kwon J T, Kim H J
Abstract excerpt
The transporter 1 ATP-binding cassette sub-family B (MDR/TAP) gene (TAP1) is located in the major histocompatibility complex class II region, and forms a heterodimer that plays a key role in endogenous antigen presentation pathways. Investigation of polymorphisms identified in these loci has revealed an association with several autoimmune disorders. Alopecia areata (AA) is a common autoimmune disease resulting...
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