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Article

Genetic variant association of PTPN22, CTLA4, IL2RA, as well as HLA frequencies in susceptibility to alopecia areata.

Immunological investigations - 1 Oct 2018

Moravvej Hamideh, Tabatabaei-Panah Pardis-Sadat, Abgoon Reyhaneh, Khaksar Leyla, Sokhandan Masumeh, Tarshaei Saba, Ghaderian Sayyed Mohammad Hossein, Ludwig Ralf J, Akbarzadeh Reza

Abstract excerpt

Alopecia areata (AA) is characterized by a genetically complex inheritance. HLA frequencies, as well as the single nucleotide polymorphism (SNP) in PTPN22, CTLA4, and IL2RA genes, have been described to be associated with AA susceptibility. So far, no independent replication of these studies has been reported, and no data exist on a possible association between AA disease and these SNPs or influence of HLA...

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Source

Identifiers

PMID: 29979892
DOI: 10.1080/08820139.2018.1480032

Genes

CTLA4
PTPN22

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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