Article
PTPN22 gene polymorphism in Egyptian alopecia areata patients and its impact on response to diphencyprone immunotherapy.
Gene - 10 Jul 2013
El-Zawahry Bakr Mohamed, Azzam Omar Ahmed, Zaki Nagla Sameh, Abdel-Raheem Heba Mohamed, Bassiouny Dalia Ahmed, Khorshied Mervat Mamdooh
Abstract excerpt
PTPN22 1858C>T gene polymorphism has been associated with several autoimmune disorders including alopecia areata. The aim of the current study was to investigate the effect of the inherited genetic polymorphism 1858C>T of PTPN22 gene on the predisposition to severe forms of alopecia areata and its effect on the response to DPC treatment. To achieve our aim, PTPN22 1858C>T genotyping was performed by PCR-based...
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