Article
Genetic evidence of TAP1 gene variant as a susceptibility factor in Indian leprosy patients.
Human immunology - 1 Jun 2013
Shinde Vidyagouri, Marcinek Patrick, Rani Deepa Selvi, Sunder Sharada Ramaseri, Arun Sundaramoorthy, Jain Suman, Nath Indira, Thangaraj Kumarasamy, Velavan T P, Valluri Vijaya Lakshmi
Abstract excerpt
The heterodimeric transporter associated with antigen processing (TAP) gene loci is known to play a vital role in immune surveillance. We investigated a possible association of gene polymorphisms both in TAP1 and TAP2 in a cohort of clinically classified leprosy patients (n=222) and in ethnically matched controls (n=223). The TAP1 and TAP2 genes were genotyped for four single nucleotide polymorphisms TAP1...
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