Article
Association of Rs231775 Genetic Variant of Cytotoxic T-lymphocyte Associated Protein 4 with Alopecia Areata Disease in Males: A Case-Control Study.
Immunological investigations - 1 Nov 2021
Ismail Nader Ali, Toraih Eman Ali, Ameen Hatem Mohamed, Gomaa Amal Hussein Ahmed, Marie Radwa El-Sayed Mahmoud
Abstract excerpt
BACKGROUND: Alopecia Areata (AA) is a common inflammatory immune-mediated non-scarring hair loss; however, the exact genetic susceptibility remains to be clarified. Cytotoxic T-lymphocyte Associated Protein 4 (CTLA4) has emerged as a central and critically important modulator of immune responses and is believed to play a crucial rule in AA pathogenesis. OBJECTIVES: To investigate the association of CTLA4 variant...
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