Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genes of the LMP/TAP cluster are associated with the human autoimmune disease vitiligo.

Genes and immunity - 1 Oct 2003

Casp C B, She J-X, McCormack W T

Abstract excerpt

Genes within the class II region of the major histocompatibility complex (MHC), including genes involved in antigen processing and presentation, have been reported to be associated with several autoimmune diseases. We report here that the LMP/TAP gene region is significantly associated with vitiligo, a disorder in which biochemical defects and/or autoimmune destruction cause melanocyte loss and resulting skin...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigen Presentation
Share to ATP Binding Cassette Transporter, Subfamily B, Member 2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Canada

Share to Cysteine Endopeptidases

Share to Genes, MHC Class II

Share to Multienzyme Complexes

Share to Proteasome Endopeptidase Complex

Share to Vitiligo

Source

Identifiers

PMID: 14551602
DOI: 10.1038/sj.gene.6364016

Genes

TAP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genes of the LMP/TAP cluster are associated with the human autoimmune disease vitiligo.PMID 14551602Read ↗

A case-control study on association of proteasome subunit beta 8 (PSMB8) and transporter associated with antigen processing 1 (TAP1) polymorphisms and their transcript levels in vitiligo from Gujarat.Semantic proximity Read ↗

Pemphigus vulgaris is associated with the transporter associated with antigen processing (TAP) system.Semantic proximity Read ↗

Strong associations of psoriasis with antigen processing LMP and transport genes TAP differ by gender and phenotype.Semantic proximity Read ↗

Distribution of HLA-A, B alleles and polymorphisms of TAP and LMP genes in Korean patients with atopic dermatitis.Semantic proximity Read ↗

Epidemiology of vitiligo and associated autoimmune diseases in Caucasian probands and their families.Semantic proximity Read ↗

Transporter TAP1-637G and immunoproteasome PSMB9-60H variants influence the risk of developing vitiligo in the Saudi population.Semantic proximity Read ↗

Association between TAP1 gene polymorphisms and alopecia areata in a Korean population.Semantic proximity Read ↗

Variant of TYR and autoimmunity susceptibility loci in generalized vitiligo.Semantic proximity Read ↗

The genetic architecture of vitiligo.Semantic proximity Read ↗

Physiopathology and genetics of vitiligo.Semantic proximity Read ↗

Six decades of vitiligo genetics: genome-wide studies provide insights into autoimmune pathogenesis.Semantic proximity Read ↗

Early disease onset and increased risk of other autoimmune diseases in familial generalized vitiligo.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.