Article
Mitochondrial ND3 G10398A mutation: a biomarker for breast cancer.
Genetics and molecular research : GMR - 21 Dec 2015
Yu Y, Lv F, Lin H, Qian G, Jiang Y S, Pang L X, Wang Y P, Wang X F, Kang Y M, Li C B, Liu Q, Xu J Z, You W
Abstract excerpt
Mitochondrial DNA mutations have been found to play important roles in carcinogenesis. The most common G10398A mutation, a non-conservative amino acid substitution from Thr to Ala, seems to be involved in the tumorigenesis of breast cancer. Results from studies concerning this mutation remain inconclusive. In the current study, we first took clinical and molecular datasets from case-control studies to determine...
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