Article
Mitochondrial NADH dehydrogenase polymorphisms are associated with breast cancer in Poland.
Journal of applied genetics - 1 May 2014
Grzybowska-Szatkowska Ludmiła, Slaska Brygida
Abstract excerpt
Complex I NADH-oxidoreductase-ubiquinone transports reducing equivalents from the reduced form of NADH to ubiquinone (coenzyme Q-CoQ). The purpose of this study was to analyze mutations in MT-ND1, MT-ND2, MT-ND3 and MT-ND6 genes and their effect on the biochemical properties, structure and functioning of proteins in patients with breast tumours. In research materials, in 50 patients, 28 total polymorphisms and...
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