Article
PREDICTING SIGNIFICANCE OF UNKNOWN VARIANTS IN GLIAL TUMORS THROUGH SUB-CLASS ENRICHMENT.
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing - 1 Jan 2016
Fichtenholtz Alex M, Camarda Nicholas D, Neumann Eric K
Abstract excerpt
Glial tumors have been heavily studied and sequenced, leading to scores of findings about altered genes. This explosion in knowledge has not been matched with clinical success, but efforts to understand the synergies between drivers of glial tumors may alleviate the situation. We present a novel molecular classification system that captures the combinatorial nature of relationships between alterations in these...
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