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Decreased expression of autophagy protein LC3 and stemness (CD44+/CD24-/low) indicate poor prognosis in triple-negative breast cancer.

Human pathology - 1 Feb 2016

Chang Shu-Jyuan, Ou-Yang Fu, Tu Hung-Pin, Lin Chih-Hung, Huang Shu-Hung, Kostoro Joanna, Hou Ming-Feng, Chai Chee-Yin, Kwan Aij-Lie

Abstract excerpt

This study evaluated the prognostic value of expression of autophagy protein light chain 3 (LC3) and the prognostic value of coexpression of LC3 and stemness markers CD44+/CD24-/low in triple-negative breast cancer (TNBC). LC3 and LC3/CD44+/CD24-/low immunophenotypes in tumor tissues were evaluated by immunohistochemistry in 67 TNBC patients. LC3- was expressed in 30 (44.78%) cases. The LC3- phenotype revealed a...

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PMID: 26772398
DOI: 10.1016/j.humpath.2015.09.034

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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