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Article

MiRNA-638 promotes autophagy and malignant phenotypes of cancer cells via directly suppressing DACT3.

Cancer letters - 1 Apr 2017

Ren Yanli, Chen Yujie, Liang Xue, Lu Yan, Pan Wenting, Yang Ming

Abstract excerpt

Dyregulation of autophagy is implicated in human cancers and the mechanism details remains largely unclear. Herein we report the regulatory role of miR-638 in autophagy of esophageal squamous cell carcinoma (ESCC) and breast cancer cells. We found that miR-638 overexpression promotes starvation- and rapamycin-induced autophagy. In ESCC and breast cancer cells, miR-638 acts as an oncogene and promotes cell...

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Source

Identifiers

PMID: 28108314
DOI: 10.1016/j.canlet.2017.01.009

Genes

DACT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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