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Article

Genome-wide methylome analysis using MethylCap-seq uncovers 4 hypermethylated markers with high sensitivity for both adeno- and squamous-cell cervical carcinoma.

Oncotarget - 6 Dec 2016

Wang Rong, van Leeuwen Robert W, Boers Aniek, Klip Harry G, de Meyer Tim, Steenbergen Renske D M, van Criekinge Wim, van der Zee Ate G J, Schuuring Ed, Wisman G Bea A

Abstract excerpt

BACKGROUND: Cytology-based screening methods for cervical adenocarcinoma (ADC) and to a lesser extent squamous-cell carcinoma (SCC) suffer from low sensitivity. DNA hypermethylation analysis in cervical scrapings may improve detection of SCC, but few methylation markers have been described for ADC. We aimed to identify novel methylation markers for the early detection of both ADC and SCC. RESULTS: Genome-wide...

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Identifiers

PMID: 27738327
DOI: 10.18632/oncotarget.12598
PMCID: PMC5348351

Genes

SOX1
SOX14
TBX20

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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