Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular Pap smear: HPV genotype and DNA methylation of ADCY8, CDH8, and ZNF582 as an integrated biomarker for high-grade cervical cytology.

Clinical epigenetics - 1 Jan 2016

Shen-Gunther Jane, Wang Chiou-Miin, Poage Graham M, Lin Chun-Lin, Perez Luis, Banks Nancy A, Huang Tim Hui-Ming

Abstract excerpt

BACKGROUND: The Pap smear has remained the foundation for cervical cancer screening for over 70 years. With advancements in molecular diagnostics, primary high-risk human papillomavirus (hrHPV) screening has recently become an accepted stand-alone or co-test with conventional cytology. However, both diagnostic tests have distinct limitations. The aim of this study was to determine the association between HPV...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenylyl Cyclases
Share to Cadherins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Early Detection of Cancer

Share to Kruppel-Like Transcription Factors

Share to Neoplasm Grading

Share to Papanicolaou Test

Share to Uterine Cervical Dysplasia

Share to Vaginal Smears

Source

Open in PubMed Open full text

Identifiers

PMID: 27651839
DOI: 10.1186/s13148-016-0263-9
PMCID: PMC5022163

Genes

ADCY8
CDH8
MGMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular Pap smear: HPV genotype and DNA methylation of ADCY8, CDH8, and ZNF582 as an integrated biomarker for high-grade cervical cytology.PMID 27651839Read ↗

Role of genomic DNA methylation in detection of cytologic and histologic abnormalities in high risk HPV-infected womenSemantic proximity Read ↗

Discovery and technical validation of high-performance methylated DNA markers for the detection of cervical lesions at risk of malignant progression in low- and middle-income countriesSemantic proximity Read ↗

Discovery and validation of candidate host DNA methylation markers for detection of cervical precancer and cancerSemantic proximity Read ↗

HPV-Driven Cervical Carcinogenesis: Genetic and Epigenetic Mechanisms and Diagnostic Approaches.Semantic proximity Read ↗

DNA methylation in human papillomavirus-infected cervical cells is elevated in high-grade squamous intraepithelial lesions and cancer.Semantic proximity Read ↗

Virtues and Weaknesses of DNA Methylation as a Test for Cervical Cancer PreventionSemantic proximity Read ↗

Genome-wide DNA methylation profiling identifies two novel genes in cervical neoplasia.Semantic proximity Read ↗

Validation of novel DNA methylation markers in cervical precancer and cancerSemantic proximity Read ↗

Clinical utility of HPV typing and quantification combined with PAX1/ZNF582 methylation detection in accurate cervical cancer screeningSemantic proximity Read ↗

Cervical dysplasia: Assessing methylation status (Methylight) of CCNA1, DAPK1, HS3ST2, PAX1 and TFPI2 to improve diagnostic accuracySemantic proximity Read ↗

DNA methylation signatures of cervical pre‐invasive and invasive disease: An epigenome‐wide association studySemantic proximity Read ↗

Utility of gene methylation analysis, cytological examination, and HPV-16/18 genotyping in triage of high-risk human papilloma virus-positive womenSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.