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Article

Alternative splicing within the Wnt signaling pathway: role in cancer development

13 Jan 2016

Abstract excerpt

BACKGROUND: The Wnt signaling cascade plays a fundamental role in embryonic development, adult tissue regeneration, homeostasis and stem cell maintenance. Abnormal Wnt signaling has been found to be prevalent in various human cancers. Also, a role of Wnt signaling in the regulation of alternative splicing of several cancer-related genes has been established. In addition, accumulating evidence suggests the...

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PMID: 26762488
DOI: 10.1007/s13402-015-0266-0

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