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Article

MMP-2 gene polymorphisms are associated with type A aortic dissection and aortic diameters in patients.

Medicine - 1 Oct 2016

Liu Ou, Xie Wuxiang, Qin Yanwen, Jia Lixin, Zhang Jing, Xin Yi, Guan Xinliang, Li Haiyang, Gong Ming, Liu Yuyong, Wang Xiaolong, Li Jianrong, Lan Feng, Zhang Hongjia

Abstract excerpt

Matrix metalloproteinases-2 (MMP-2) plays an important role in the pathogenesis of type A aortic dissection (AD). The aim of this study was to evaluate the association of 3 single nucleotide polymorphisms (SNPs) in the MMP-2 gene with type A AD risk and aortic diameters in patients. We performed a case-control study with 172 unrelated type A AD patients and 439 controls. Three SNPs rs11644561, rs11643630, and...

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Identifiers

PMID: 27759651
DOI: 10.1097/MD.0000000000005175
PMCID: PMC5079335

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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