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Article

Variants of genes encoding collagens and matrix metalloproteinase system increased the risk of aortic dissection.

Science China. Life sciences - 1 Jan 2017

Li Zongzhe, Zhou Chengming, Tan Lun, Chen Peng, Cao Yanyan, Li Chenze, Li Xianqing, Yan Jiangtao, Zeng Hesong, Wang Dao-Wu, Wang Dao-Wen

Abstract excerpt

Aortic dissection (AD) is a devastating, heterogeneous condition of aorta. The homeostasis between collagens and matrix metalloproteases (MMPs)/tissue inhibitors of MMPs (TIMPs) system in the extracellular matrix plays an important role for structure and functions of aorta. However, our knowledge on association between variants of genes in this system and pathogenesis of AD is very limited. We analyzed all yet...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27975164
DOI: 10.1007/s11427-016-0333-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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